The search was done in electronic databases of PubMed, Scopus, ScienceDirect, Web of Science and Google Scholar for studies using the key terms: Cissus quadrangularis, antimicrobial, anti-obesity, anti-inlammatory, bone resorption and antioxidant. It is a well-recognized plant in the conventional system of medicine in India for treating bone . Methods: All men received CQ 3200 mg daily for 8 weeks. Asthishnkhal (Cissus quadrangularis Linn) A New Emerging Medicine for Osteoarthritis: A Review Author: Rashmi Kathait1 . I know I need it, but I've subconsciously gotten "ab anxiety" and I'm afraid to lose my six pack I worked so hard to get sometimes I wonder if any of this is worth the mental stress M / 32yo / 145 pounds / pic below of current physique. Named for its four-sided shaped stem, extracts from this plant have been used in traditional Thai, African, and Ayurvedic medicine for centuries to treat various ailments. In Ayurvedic medicine, it is a popular remedy for broken bones. This alone makes Core SOOTHE a game-changer, and one you should try if you're looking for some different results. https://pubmed.ncbi.nlm.nih.gov/22976133/ Jadhav AN . Cissus quadrangularis Linn. Cissus quadrangularis (CQ) is a succulent plant of the. The plant Cissus quadrangularis (CQ) (Veldt Grape or Winged tree-bine), a climber belonging to the family Vitaceae, has been used as an osteogenic/osteoprotective medicine in Ayurveda. In India, CQ is one of the widely used medicinal plants. Infrared (IR), vibratory bed assisted infrared (VIR), vacuum infrared (VC-IR), and vibratory bed assisted vacuum infrared (VC-VIR) drying of Cissus quadrangularis Linn. Cissus quadrangularis L. (Cissus) is a medicinal plant commonly used for centuries for various conditions, but lacks critical appraisal of its clinical effects. It is still unclear which compounds are the active ingredients for bone formation. Introduction: Cissus quadrangularis Linn. Cissus Quadrangularis has also been linked for weight loss! Cissus quadrangularis, Vitacea, has a succulent stem and shows Crassulacean Acid Metabolism (CAM).Environmental control of CAM is shown with respect to water supply, day temperature, and light intensity. Cissus quadrangularis L. (CQ, Family Vitaceae) is one of the most frequently used medicinal plants widely distributed in India, Africa, Arabia and IndoMalaysia 4. 2021). . PubMed: https://pubmed.ncbi.nlm.nih.gov/16948861/ The Wealth of India, A Dictionary of Indian Raw Materials . The effect of Cissus quadrangularis (CQR-300) and a Cissus formulation (CORE) on obesity and obesity-induced oxidative stress. Nutrakey's Cissus Quadrangularis is 100% Natural, contains no fillers, and is Non-GMO. Keywords. It has been far too long since we've written about cissus quadrangularis, which was an incredibly popular anti-inflammatory joint and bone health supplement in the 2000s that disappeared for no reason whatsoever. Laura Sisti et al. It is usually seen in hot climate in various states of India, Sri Lanka, Malaya, Java, and West Africa [ 27 ]. It is believed to be native to either Sri Lanka or India but is also found within Arabia, Southeast Asia, and Africa. The medicinal value of plants is due to the presence of particular chemical substances that have a definite physiological action on the living system. This report highlights phytoconstituents present in Cissus quadrangularis (CQ) extract and examines biphasic (proliferative and anti-proliferative) effects of its extract on bone cell proliferation, differentiation, mineralization, ROS generation, cell cycle progression and Runx2 gene expression in primary rat osteoblasts. Clinical evaluation of cissus quadrangularis and moringa oleifera and osteoseal as osteogenic agents in mandibular fracture Vibha Singh 1, Narendra Singh 2, US Pal 1, Satish Dhasmana 3, Shadab Mohammad 1, Nimisha Singh 1 . Out of these, 8 genera and 63 different species are found in India ( Ansarali et al., 2016 ). Cissus Quadrangularis, (a key ingredient in IGNITE ) is a perennial plant that is part of the grape family. The present study was employed to delineate the effects of ethanolic extract of C. quadrangularis on . Though almost all of its parts are used in traditional systems of medicines . It has also been imported to the southern United States and Brazil. Cissus quadrangularis, a medicinal plant indigenous to Asia and Africa, is used for many ailments, especially for the treatment of hemorrhoid. Cissus quadrangularis is an ancient medicinal plant native to the hotter parts of Ceylon and India. . [SCOPUS][CROSSREF][PUBMED] A study was undertaken to evaluate the effect of methanolic extract of Cissus quadrangularis Linn (CQ) on the healing process of experimentally fractured radius-ulna of dog. Objective: The study was designed to investigate the hepatoprotective activity of methanol extract of Cissus quadrangularis (CQ) against isoniazid-induced hepatotoxicity in rats. The extract is taken from a plant found in parts of Asia, including India, Malaysia, Thailand and Sri Lanka. 2016; 5: 24-29. ago. Introduction: In ancient times Cissus quadrangularis Linn. Significant cellular toxicity was observed with >75 g/mL CVE. After completing distractor activation, patients were randomly divided into two equal groups according to administered drug . Cissus Quadrangularis is an African plant which has long been used in traditional medicine by tribesman for a wide range of benefits including supporting the bones, joints, and cartilage in the body. It is one of the most commonly used medicinal plants in Thailand, and is also used in traditional African and Ayurvedic. . Abstract. Publications from 12 electronic databases were searched from inception through November 2016. The stem of C. quadrangularis has a wide range of applications in both human and animal medicine, but there is limited cytogenetic information available for this species. In this present investigation, we report the green nanoparticles prepared by using stem extract of Cissus quadrangularis and assess the physical and chemical factors such as time duration, metal ion concentration, pH, and temperature that play vital role in the nanoparticles synthesis . 6 , 4 (2007). Cissus Quadrangularis is a herbal extract found in traditional medicine that is often used to treat joint and bone health, along with female health issues including the menopause and libido problems. Traditional use of Cissus quadrangularis (C. quadrangularis) in the treatment of bone disorders has been documented. Material and methods Twenty patients with atrophic ridge were treated by alveolar distraction. Nootropics Depot Guru. VC-VIR drying of 5-mm CQ provided the highest maximum drying rate (DR) of 0.258 g water/g dry . Cissus Quadrangularis is an African plant which has long been used in traditional medicine by tribesman for a wide range of benefits including supporting the bones, joints, and cartilage in the body. aim of the review a organized summary of the botany,. From, total 408 records of this herb, we have screened 155 articles consist of desired information and available as full text. has been implicated as therapeutic agent for enhancing bone healing. It has been used by common folk in India for promoting the fracture healing process. Its primary use has been to help heal broken bones and injured ligaments & tendons. OBJECTIVES Hyperglycemia-induced SIRT1, DNMT1, SODs, as well as oxidative stress, play a pivotal role in the progression of diabetic nephropathy. Other common names include veldt grape, devil's backbone, and adamant creeper. Cissus quadrangularis Linn. The results indicated that . (CQ) has been used in Indian and Thai traditional medicine for healing bone fractures because of numerous active ingredients in CQ. Cissus quadrangularis a succulent vine belongs to Vitaceae family is widely distributed throughout tropical and subtropical regions of the world and used frequently to various disorders. The purpose of the present study was to investigate the use of a Cissus quadrangularis formulation in the management of metabolic syndrome, particularly weight loss and central obesity. CVE treatment at 50 g/mL ameliorated H2O2-induced . 45. r/fitness30plus. It has been used to treat an array of health conditions for centuries, and, today, its extracts are widely available as. Cissus quadrangularis, holds antioxidant and hypoglycemic . The plant. Clinics 64 993-998 In the present study, the effects of ethanol extract of C. quadrangularis (CQ-E) on osteoblast differentiation and function were analyzed using murine osteoblastic cells. PubMed PubMed Central Article Google Scholar Potu BK, Bhat KMR, Rao MS, Nampurath GK, Chamallamudi MR, Nayak SR and Muttigi MS 2009 Petroleum ether extract of cissus quadrangularis (linn.) It was prescribed in the ancient Ayurvedic texts as a general tonic and analgesic, with specific bone fracture healing properties. Traditional use of Cissus quadrangularis (C. quadrangularis) in the treatment of bone disorders has been documented. . 75. databases PubMed, Scopus, ScienceDirect, Web . PMID: 18377661 [PubMed - indexed for MEDLINE] ----- 2007 Feb 4;6:4 The effect of Cissus quadrangularis (CQR-300) and a Cissus formulation (CORE) on obesity and obesity-induced oxidative stress. It is popular as a joint aid for athletes, with preliminary evidence supporting this property of cissus. Modern research has shed light on Cissus' ability to speed bone healing by showing it acts . Cissus quadrangularis is an ancient medicinal plant native to the hotter parts of Ceylon and India. For a review of the literature, various databases were searched, including PubMed, EMBASE, and Scopus etc. Cissus quadrangularis is a perennial plant of the grape family. Fracture of maxillofacial skeletal takes reasonably long time to heal. 9 mo. PubMed Central CAS Article PubMed Google Scholar Furukawa S, Fujita T, Shimabukuro M, Iwaki M . Cissus quadrangularis, HPLC, phytosterols. enhances bone marrow mesenchymal stem cell proliferation and facilitates osteoblastogenesis. It has also been imported to the southern United States and Brazil. The stout fleshy stem of C. quadrangularis is an edible plant found throughout the hotter parts of India, Malaya, West Africa, and Ceylon. Studies suggest that Cissus Quadrangularis helps with bone and tissue repair with some studies demonstrating a positive impact on pain, swelling, and mobility. MATERIALS AND METHODS (CQ) were conducted. In Ayurveda, its usage in the treatment of bone fractures and swelling has been mentioned [ 28 ]. The aim of this study was to compare the effect of a proprietary extract of Cissus quadrangularis (CQR-300) to that of a proprietary formulation containing CQR-300 (CORE) on weight, blood lipids, and oxidative stress in overweight and obese people. Though its osteogenic activity has been suggested, the underlying mechanism still remains unclear. The present work is an attempt to use Cissus quadrangularis plant leaf extract and Piper betle leaf extract as a bio-reductant for green and rapid synthesis of CuO NPs by using copper sulphate as the parent material. The repair of bone defect is still a big challenge for orthopedic surgeons. It contains a lot of vitamin C and antioxidants. It is still unclear which compounds are the active ingredients for bone formation. Unfortunately we don't have an update on Cissus Quadrangularis at this time, but we are still looking into it. Cissus is a genus of the Vitaceae family consisting of 800 species divided into 13 genera throughout the world, including Africa, Arabia, South Asia, Srilanka, India and other tropical regions. The present study was employed to delineate the effects of ethanolic extract of C. quadrangularis on the proliferation, differentiation and matrix mineralization of human osteoblast like SaOS-2 cells. Super Cissus contains Cissus Quadrangularis Extract, which is a plant from Africa that has been used in medicine. Phytosynthesis process of silver nanoparticles using plant extract is simple, cost-effective, and ecofriendly. [ 17] Cissus quadrangularis uses are known to . Cissus quadrangularis is a vine that grows in Africa and parts of Asia. CQ treated animals revealed faster initiation of healing process than the control animals on radiological and histopathological examinations. . https://pubmed.ncbi.nlm.nih.gov/22976133/ Jadhav AN . this herb is documented to possess a wide-ranging ethnomedicinal uses in malaria, fever, epilepsy, gout, piles, skin diseases, colic, etc. Cissus quadrangularis is a plant that's rich in vitamin C and antioxidants. [ 16] This plant grows in the hotter regions of India, Sri Lanka, Malaysia, Java and West Africa. Cissus quadrangularis (CQ) is a medicinal herb used in Siddha and Ayurvedic medicine since ancient times in Asia, as a general tonic and analgesic, especially for bone fracture healing [ 5 ]. The studies on Cissus quadrangularis Linn. However, cissus has applications that extend past these. Genus Cissus belongs to the grape family, Vitaceae and the members of this taxon are important source of resveratrol, a phenolic secondary metabolite. The purpose of our study was to determine the therapeutic effects of CQ supplementation in healthy, exercise-trained men with joint-specific pain. Cissus quadrangularis Linn. Cissus quadrangularis, holds antioxidant and hypoglycemic activity; however, a direct link between its activity and prevention of diabetic nephropathy has not been ascertained yet. C. quadrangularis, under moderate drought, has a high capacity for dark CO 2 fixation and high efficiency of water use (nocturnal transpiration ratio = 8). METHODS: The study was a randomized, double-blind, placebo-controlled design involving 123 overweight and obese persons (47.2% male; 52.8% female; ages 19-50). . The molecular mechanism . Cissus quadrangularis grows in many areas of Asia and has long . What is Super Cissus good for? Osteoporosis is a public health problem which is associated with significant morbidity and mortality. It is a fleshy, cactus-like liana widely used as a food item in India [].The plant is prescribed in the ancient Ayurvedic literature as a general tonic and analgesic, with specific bone fracture . Cissus quadrangularis (CQ) is a climbing shrub, which belongs to the Vitaceae family. Dosage Examine Database Cissus quadrangularis, a member of the grape family, is a plant native to Asia and Africa. In this study, the synthesis of . Nicknamed "bone-setter", it has been used for . To evaluate the effects of two formulations, Cissus quadrangularis-only and a Cissus quadrangularis/Irvingia gabonensis combination, on weight loss in overweight and obese human subjects. . The formation of CuO NPs was primarily confirmed by the colour change of the attained solution. Int J Ayu Pharm Chem ISSN 2350-0204 www.ijapc.com REVIEW ARTICLE May 10th 2022 Volume 16, Issue 3 Page 81 Cissus Quadrangularis, (a key ingredient in IGNITE ) is a perennial plant that is part of the grape family. This study aimed to determine the efficacy and safety of Cissus in all conditions. Recently, various extraction and analytical systems have been developed to study herbal components of its extract as well as its pharmacological activities. Nicknamed "bone-setter", it has been used for . Aim Once considered a problem of developed countries, obesity and obesity-related complications (such as metabolic syndrome) are rapidly spreading around the globe. [PUBMED] DOI: 10.4103/2348-0149.135730 Abstract : Introduction: In ancient times Cissus . Abstract. The studies declared that there was a noticeable amount of weight loss in almost 123 overweight persons." . It has a history of being used in various Ayurvedic classical medicines. The study was a 10 week randomized, double-blind, placebo-controlled design involving 72 obese or overweight participants (45.8% male; 54.2% female; ages 21-44; mean age = 29.3). It was . Cissus quadrangularis L. (Vitaceae) is a common perennial climber, which is distributed throughout Bangladesh. are extensive, but gaps still remain. Methods G. Manimekalai et al., reported that the thermal stability of the cellulosic stem fiber from Cissus quadrangularis plantis improved when extracting fibers by enzymes (Manimekalai et al. Methods The study was a randomized, double . Cissus supplementation may also assist in weight loss,, lowering . The objective was to investigate the effects of vibration, vacuum, and material thickness on IR drying of CQ. The inclusion was based reported articles on pharmacological activities of C. quadrangularis Cissus quadrangularis (CQ) has been reported to have anti-inflammatory activity. Cissus quadrangularis L. (CQ), a succulent plant of the family Vitaceae, is commonly found in tropical and subtropical xeric woods. Incubation with CVE produced concentration-dependent toxicity in HT22 cells. Cissus Quadrangularis Cissus quadrangularis is a traditional medicine for joint and bone health (as well as various feminine disorders and menopause), and shows promise in promoting bone growth rates. . Cissus quadrangularis (Vitaceae) is a perennial climber endemic to Africa and is characterized by succulent angular stems. Pharmacological investigations on the anti-osteoporotic and anti-inflammatory activities of Cissus quadrangularis L. substantiate the scientific basis of using this plant to treat fractured bone . Materials and Methods: The successive petroleum ether (60-80C) and methanol extracts of C. quadrangularis were used. Treatment with EECQ demonstrated substantial attenuation of elevated insulin resistance, lipid profile and creatinine level, and shows a protective effect against diabetic nephropathy in rats. https://pubmed.ncbi.nlm.nih.gov/22976133/ Sawangjit R, Puttarak P, Saokaew S . Cissus quadrangularis a succulent vine belongs to Vitaceae family is widely distributed throughout tropical and subtropical regions of the world and used frequently to various disorders. The plant grows in arid and semi-arid regions of Africa especially in the African savanna. The molecular docking technique, the ethanolic extraction along with hexane fractionation, and an in vitro experiment with a human osteoblast cell line . It can be used to support bone health and reducing the joint pain by reducing inflammation. reported, also, a certain shift of the degradation onset temperature and of temperature of the maximum degradation onset towards high . is an indigenous medicinal plant, grown in India, which helps to increase healing process of fractured bone. Cissus quadrangularis. Lipids in Health and Disease. wa s used as a general chow item in China. One of the herbs that have shown beneficial effects on bone belongs to the Cissus family of plants. In the present study, we examined the effects of Cissus verticillata leaf extracts (CVE) against hydrogen peroxide (H2O2)- and ischemia-induced neuronal damage in HT22 cells and gerbil hippocampus. Extracts and powders of Cissus quadrangularis have been used for many years to promote bone and tissues healing, as an analgesic, to treat infections, as an anabolic, and to promote weight loss and weight management. Cissus quadrangularis, etc ; bone density; bone resorption; collagen; femur; lumbar spine; osteopenia; osteoporosis; placebos; postmenopause; risk; Show all 11 Subjects Abstract: Osteopenia refers to bone density that is not normal but also not as low as that noted in osteoporosis. Background This randomized clinical trial was designed to evaluate osteogenic potential of Cissus quadrangularis in alveolar distraction to facilitate implant installation. (CQ) has been used in Indian and Thai traditional medicine for healing bone fractures because of numerous active ingredients in CQ. Many attempts have been made till today to reduce the healing period of 6-8 weeks, by means of improved surgical technology or by inhibiting the physiological mechanism of . A number of cultures have long prized C. quadrangularis as a medicinal plant. The purpose of the present study was to investigate the use of a Cissus quadrangularis formulation in the management of metabolic syndrome, particularly weight loss and central obesity. Clinical evaluation of Cissus quadrangularis as osteogenic agent in maxillofacial fracture: A pilot study Authors Hemal R Brahmkshatriya 1 , Kruti A Shah 1 , G B Ananthkumar 1 , Mansi H Brahmkshatriya 2 Affiliations 1 Department of Oral and Maxillofacial Surgery, K. M. Shah Dental College and Hospital, Vadodara, Gujarat, India. [SCOPUS][CROSSREF][PUBMED] DOI: 10.4103/0975-5950.94466 NutraKey Cissus helps support joint health, improve joint comfort, and is a pure formula with no fillers. Article Google Scholar Join. Resveratrol is a high value bioactive compound and its medicinal properties are well established ranging from cardioprotection to chemoprotection [1, 2].Cissus qudrangularis L. and C. rotundifolia (Forsk.) This study aimed to determine the . Lipids Health Dis. Cissus quadrangularis L. (Cissus) is a medicinal plant commonly used for centuries for various conditions, but lacks critical appraisal of its clinical effects. The Cissus quadrangularis (CQ) stem has interesting nutritional and pharmacological properties to promote the health of the skeletal system. The search was done in electronic databases of PubMed, Scopus, ScienceDirect, Web of Science and Google Scholar for studies using the key terms: Cissus quadrangularis, antimicrobial, anti-obesity, anti-inflammatory, bone resorption and antioxidant.The inclusion was based reported articles on pharmacological activities of C. quadrangularis which are discussed in detail. Nutrakey's Cissus Quadrangularis is 100% Natural, contains no fillers, and is Non-GMO.
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